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KMID : 0388220090160030228
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Journal of the Korean Rheumatism Association
2009 Volume.16 No. 3 p.228 ~ p.231
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Long Term Use of Glucocorticoid Induced Osteoporotic Multiple Compression Fractures in Autoimmune Diseases
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Park Ye-Soo
Seo Wan-Sik
Cho Jae-Lim
Kim Tae-Hwan
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Abstract
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Reduced bone mineral density precedes the development of vertebral fractures in patients under long term glucocorticoid therapy. Osteoporosis is a frequent complication in steroid- dependent patients, and the risk of developing vertebral fractures in these patients is much higher than involutional osteoporosis. We described a 54-year-old patient who presented with autoimmune hepatitis and had a 6-year history of steroid medication. The patient had multiple compression fractures (T10∼L5) without trauma, and was treated successfully with multi-level vertebroplasty and an intravenous injection of bisphosphonate without complications.
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KEYWORD
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Autoimmune disease, Steroid, Osteoporotic vertebral fracture
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